These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: HLA-DRw7 and steroid-responsive nephrotic syndrome of childhood.
    Author: Alfiler CA, Roy LP, Doran T, Sheldon A, Bashir H.
    Journal: Clin Nephrol; 1980 Aug; 14(2):71-4. PubMed ID: 6931666.
    Abstract:
    We searched for possible immunogenetic markers in steroid-responsive nephrotic syndrome of childhood (SRNS). The incidence of HLA-DRw7 was significantly greater in SRNS patients than in controls (71% in patients, 29.8% in controls, P < 0.005). The HLA-A and -B locus antigens occurred in normal frequencies. The relative risk factor for HLA-DRw7 in SRNS was 5.9. This report failed to show a relationship between HLA-DRw7 and atopy, use of alkylating agents or occurrence of relapse after remission induced by these agents. We believe that SRNS may be an immunologic disorder whose pathogenesis is related to an MHC-linked Ir gene.
    [Abstract] [Full Text] [Related] [New Search]