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  • Title: Anticaries and antiplaque potential of free-fatty acids in vitro and in vivo.
    Author: Schuster GS, Dirksen TR, Ciarlone AE, Burnett GW, Reynolds MT, Lankford MT.
    Journal: Pharmacol Ther Dent; 1980; 5(1-2):25-33. PubMed ID: 6932048.
    Abstract:
    The efficacy of several fatty acids as antimicrobial, antiplaque, and anticaries agents, as well as their ability to inhibit hydroxyapatite dissolution were examined. All effectively inhibited bacterial growth. Lauric, linoleic, and oleic acids decreased plaque formation and lauric acid inhibited hydroxyapatite dissolution. When used in the food, lauric acid decreased caries in rats, but not significantly.
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