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  • Title: Gonadal infiltration in children with leukaemia and lymphoma.
    Author: Reid H, Marsden HB.
    Journal: J Clin Pathol; 1980 Aug; 33(8):722-9. PubMed ID: 6933154.
    Abstract:
    In a postmortem survey of children with leukaemia and lymphoma, the overall incidence of testicular infiltration was 65% and of ovarian infiltration 66%. In acute lymphoblastic leukaemia, testicular infiltration was found in 25 of 39 cases and ovarian infiltration in 6 of 12 cases. The majority of boys with acute lymphoblastic leukaemia and testicular infiltration also had infiltration in other organs; furthermore, in most cases without testicular infiltration leukaemic infiltration was found in other organs. The findings of this survey support the view that testicular infiltration is indicative of widespread disease.
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