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  • Title: Rapid quantitative determination of the effect of antiplaque agents and antisera on the growth, acid production, and adherence of Streptococcus mutans.
    Author: Ciardi JE, Rosenthal AB, Bowen WH.
    Journal: J Dent Res; 1981 Mar; 60(3):756-62. PubMed ID: 6937511.
    Abstract:
    A rapid quantitative in vitro assay measured the effects of antiplaque agents and antiserum on growth and sucrose-mediated adherence of radio-labeled S. mutans 6715. Acid production was measured by change in pH. In this assay the primary effect of chlorhexidine and fluoride was bacteriostasis and inhibition of acid production, respectively; the primary effect of dextran, dextranase, and specific antiserum was inhibition of sucrose-mediated adherence.
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