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  • Title: Rifampicin associated renal dysfunction during antituberculous therapy.
    Author: Need AG, Phillips PJ, Chiu FT, Clarkson AR.
    Journal: Aust N Z J Med; 1980 Dec; 10(6):657-9. PubMed ID: 6938187.
    Abstract:
    Intermittent rifampicin therapy has been reported to commonly cause a flu-like illness with chills and fever sometimes associated with acute renal failure. This report describes a fourth case of partially reversible insidious renal damage associated with continuous rifampicin therapy and provides evidence that it is not the results of light chain proteinuria as previously suggested. A retrospective review of data relating to renal function in 89 tuberculous patients indicated that increased plasma urate concentration was commonly associated with ethambutol therapy.
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