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  • Title: Friend murine leukemia virus resistance in Japanese wild mice: possible allelism with Fv-4 in FRG mice.
    Author: Suzuki S, Tsuji K, Moriwaki K.
    Journal: J Natl Cancer Inst; 1981 Apr; 66(4):729-31. PubMed ID: 6939918.
    Abstract:
    A dominant gene (Rm) for resistance to ecotropic murine leukemia virus was found in Japanese wild mice (Mn) and was similar to the FV-4 gene in inbred FRG mice. About one-fourth of the progeny of the cross (BALB/c x Mn) x (FRG x BALB/c) produced only resistant progeny when crossed to BALB/c mice, which indicated that Rm and Fv-4 are at the same chromosomal location. This evidence for allelism was confirmed by the finding that matings of BALB/c mice partially congenic for Rm or for Fv-4 yielded progeny that produced only resistant offspring when crossed to BALB/c mice.
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