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  • Title: Results at 5 years of a controlled comparison of a 6-month and a standard 18-month regimen of chemotherapy for pulmonary tuberculosis.
    Journal: Am Rev Respir Dis; 1977 Jul; 116(1):3-8. PubMed ID: 69411.
    Abstract:
    The relapse rate up to 5 years after the start of chemotherapy with a 6-month regimen of daily streptomycin, isoniazid, and rifampin has been compared with the rate for a standard 18-month regimen of streptomycin, thiacetazone, and isoniazid for 2 months, followed by thiacetazone and isoniazid for 16 months daily. There were 5 bacteriologic relapses in 145 patients on the 6-month regimen, 1 occurring between 3 and 5 years after admission compared with 3 in 125 patients on the 18-month regimen, 1 occurring between 3 and 5 years.
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