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  • Title: "Masked" philadelphia chromosome (Ph1) due to an unusual translocation.
    Author: Marinello MJ, Morita M, Sandberg AA.
    Journal: Cancer Genet Cytogenet; 1981 Apr; 3(3):227-32. PubMed ID: 6945148.
    Abstract:
    The case of a 58-year-old white female with Philadelphia (Ph1)-positive chronic myelocytic leukemia (CML) and a "masked" Ph1 chromosome is described. The Ph1 was due to a translocation involving chromosomes #12 and #22, in which most of the long arm of #12 had been translocated to the deleted #22 (Ph1). The necessity of performing banding analysis in those cases of CML where a Ph1 is not readily apparent is stressed and the literature on"masked" Ph1 chromosomes is briefly summarized.
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