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Title: Generalised glycogenosis in Brahman cattle. Author: O'Sullivan BM, Healy PJ, Fraser IR, Nieper RE, Whittle RJ, Sewell CA. Journal: Aust Vet J; 1981 May; 57(5):227-9. PubMed ID: 6945845. Abstract: Generalised glycogenosis was diagnosed in Brahman cattle on 4 Queensland properties on the basis of clinical observations and pathological and biochemical findings. The disease presented as a problem of ill-thrift and poor growth rate in calves which eventually showed nervous signs. Histologically there was vacuolation in the cells of the central nervous system, heart and muscular tissues. Biochemical assay of liver and blood mononuclear cells demonstrated a deficiency of alpha-glucosidase. Parents of affected calves had approximately half the alpha-glucosidase activity of that found in normal cattle.[Abstract] [Full Text] [Related] [New Search]