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  • Title: 13-cis-retinoic acid: effect on urinary bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in Fischer rats.
    Author: Croft WA, Croft MA, Paulus KP, Williams JH, Wang CY, Lower GM.
    Journal: Cancer Lett; 1981 May; 12(4):355-60. PubMed ID: 6946855.
    Abstract:
    The failure of 13-cis-retinoic acid to inhibit either the incidence or severity of bladder carcinoma in female Fischer rate initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide (FANFT) suggests that inhibition of bladder carcinogenesis by natural and synthetic retinoids is carcinogen-class specific, and adds an element of complexity to approaches in chemoprevention.
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