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  • Title: Three cases of hemoglobin O Arab.
    Author: Penev MN, Panova DY, Ivanov BN.
    Journal: Folia Haematol Int Mag Klin Morphol Blutforsch; 1977; 104(2):271-6. PubMed ID: 69591.
    Abstract:
    Three new cases of Hb 0 Arab in two families are reported from districts of Bulgaria, where a carrier state of this abnormal hemoglobin has not been established so far. One of the propositi is a double heterozygote for Hb 0 Ar/beta(0)-thalassemia. His father is a simple heterozygote for Hb 0 Ar with clear-cut cytomorphological stigmata, indicating hemoglobinosis. The second propositus, according to clinical and laboratory data is also a double heterozygote for Hb 0 Ar and beta(0)-thalassemia. The carriers investigated are of Bulgarian nationality. Their territorial origin supportsthe thesis that the gene mutation for Hb 0 Arab most probably has taken place out of the present boundaries of Bulgaria.
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