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  • Title: Chromogenic peptide substrate assays in patients with multiple trauma.
    Author: Kierulf P, Aasen AO, Aune S, Godal HC, Ruud TE, Vaage J.
    Journal: Acta Chir Scand Suppl; 1982; 509():69-72. PubMed ID: 6962622.
    Abstract:
    Daily monitoring of the plasma proteolytic enzyme systems i.e. the coagulation, the fibrinolytic and the kallikrein-kinin system in multitraumatized patients with chromogenic substrate assays disclosed significant differences in the levels of Prekallikrein, Hageman Factor, Antithrombin-III, Prothrombin in survivors (N = 9) and fatal cases (N = 6) during the first week after admission. Since chromogenic peptide substrate assays are simple, cheap and easily automated, close monitoring of critical care patients may be rewarding.
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