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  • Title: HL-A antigen frequency distribution in patients with gestational choriocarcinoma and their husbands.
    Author: Berkowitz RS, Hornig-Rohan J, Martin-Alosco S, Klein S, Goldstein DP, Bast RC, DeWolf WC.
    Journal: Placenta Suppl; 1981; 3():263-7. PubMed ID: 6963960.
    Abstract:
    HL-A (A,B,C, and DR) antigen frequency distribution was determined in 29 patients with choriocarcinoma and in their husbands, as well as in a matched control population of 21 healthy couples. All 29 patients had achieved complete sustained remission with chemotherapy. The HL-A antigen frequency distribution was normal in the choriocarcinoma patients and in their husbands and there was no abnormal HL-A antigen sharing between patients and their husbands. This study does not exclude the possibility that the pathogenesis of resistant choriocarcinoma may be dependent upon tumour-host histocompatibility.
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