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  • Title: Rheumatoid arthritis and B lymphocyte alloantigen HLA-DRw4.
    Author: Scherak O, Smolen JS, Mayr WR.
    Journal: J Rheumatol; 1980; 7(1):9-12. PubMed ID: 6965505.
    Abstract:
    Forty Caucasian patients with classical or definite rheumatoid arthritis were tested for 7 HLA-DR alloantigens and 37 HLA-A, B, and C antigens and compared with 125 and 450 healthy controls, respectively. HLA-DRw4 was significantly (corrected p = 10(-3) increased in rheumatoid arthritis (55%) compared with controls (23%). There was no significant correlation between clinical, radiological or serological disease parameters and HLA-DRw4. The frequency of HLA-B8 was increased in the patient group; however, the corrected p value was not significant.
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