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  • Title: Cytochemical study of thymocytes and T lymphocytes.
    Author: Basso G, Cocito MG, Semenzato G, Pezzutto A, Zanesco L.
    Journal: Br J Haematol; 1980 Apr; 44(4):577-82. PubMed ID: 6966508.
    Abstract:
    Fetal and postnatal thymocytes and circulating T lymphocytes were evaluated for six cytochemical reactions. Acid phosphatase activity was present in a high percentage of cells in all threee groups. Beta-glucoronidase and alpha-naphthyl acetate acid esterase were negative in the most immature fetal thymocytes, but become increasingly positive with T-cell maturation. Only the circulating lymphocytes presented a high percentage of N-acetyl beta glucosaminidase, alpha-naphthyl acetate esterase and alpha-naphthyl butyrate esterase positive cells. This study discusses the presence of these enzymes as proportional to different stages in T-cell maturation, and also of certain cytochemical phenotypes characteristic of these stages.
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