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  • Title: [Effect of exposure to stress on the role of T- and B-lymphocytes in the response of the hematopoietic system].
    Author: Gorizontov PD, Fedotova MI, Belousova OI, Khaitov RM, Chermeneva LI.
    Journal: Biull Eksp Biol Med; 1980 Apr; 89(4):415-7. PubMed ID: 6966945.
    Abstract:
    Cellular composition of the bone marrow, spleen and peripheral blood was studied after 6-hour immobilization on the back in experiments on 4 groups of (CBAxC57BL)F1 mice with varying degree of T lymphocyte deficiency (thymectomy, sham thymectomy, administration of antilymphocytic serum, B mice). The evidence obtained shows that the "lymphoid peak" recorded in the bone marrow during stress is likely to be formed at the expense of T and B lymphocyte migration from the peripheral lymphoid organs. The data have been also obtained, indicating that T lymphocytes migrating to the bone marrow during the first 6-9 hours after the exposure to stress may participate in granulocytopoiesis activation.
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