These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Immune condition in patients with Hodgkin's disease.
    Author: Zywicka-Lopaciuk H, Konopka L, Traczyk Z, Pawelski S, Sylwestrowicz T, Maślanka K, Arczyńska-Brojer E, Cieśluk S, Karpowicz M, Małkowska-Zwierz W.
    Journal: Arch Immunol Ther Exp (Warsz); 1980; 28(1):153-60. PubMed ID: 6968189.
    Abstract:
    In 40 cases of Hodgkin's disease (24 untreated patients and 16 patients in remission) the immunological humoral and cell-mediated competence was studied using test of hypersensitivity of DNCB and PPD, blastic transformation and the ability of 3H-DNA synthesis in lymphocytes stimulated with PHA and PWM, and in some cases, with PPD. In all patients the concentration of serum immunoglobulins was determined as well. Impairment of immunological reactivity was found in about 40% of patients, on the average, in various stages of the disease and during remissions following treatment with cytostatic agents and radiotherapy. The most frequent abnormality found in 52.5% of cases was impairment of blastic transformation of lymphocytes stimulated with PHA in vitro. In 60% of cases negative results of intradermal test with PPD and in 75% of patients the DNCB test was negative. No correlation could be found between impairment of the immune competence in this disease and the clinical stage and/or type of histological changes in lymph nodes.
    [Abstract] [Full Text] [Related] [New Search]