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  • Title: Inhibitors of fibrinolysis in amniotic fluid.
    Author: Walker JE, Campbell DM, Ogston D.
    Journal: Thromb Haemost; 1980 Aug 29; 44(1):32-4. PubMed ID: 6968460.
    Abstract:
    Amniotic fluid inhibited the fibrinolytic, amidolytic and esterolytic activity of urokinase. Kinetic studies with AGLMe demonstrated non-competitive inhibition. A major part of the inhibitory activity could be separated from alpha 1-antitrypsin by ion-exchange chromatography on DEAE-Sephadex A-50. Plasminogen activator prepared from porcine heart was not inhibited by amniotic fluid. Amniotic fluid also inhibited the caseinolytic and amidolytic activities of plasmin.
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