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  • Title: Electrical stimulation of the central gray for pain relief in human: autopsy data.
    Author: Gybels J, Dom R, Cosyns P.
    Journal: Acta Neurochir Suppl (Wien); 1980; 30():259-68. PubMed ID: 6970503.
    Abstract:
    Anatomopathological studies are reported of 5 brains in which electrical stimulation of the periventricular--periaqueductal gray was applied for the treatment of chronic pain. It was found that the recommended target was reached in 4 cases (only 1 case out of 5 was successful as far as a pain relief is concerned). PtIr electrodes caused little tissue reaction. The chronic stimulation had not provoked lesions observable by light-microscopy.
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