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  • Title: Circulating concentrations of specific placental proteins (human chorionic gonadotropin, pregnancy-specific beta-1 glycoprotein, and placental protein 5) in untreated gestational trophoblastic tumors.
    Author: Lee JN, Salem HT, Al-Ani AT, Chard T, Huang SC, Ouyang PC, Wei PY, Seppälä M.
    Journal: Am J Obstet Gynecol; 1981 Mar 15; 139(6):702-4. PubMed ID: 6971058.
    Abstract:
    Serum levels of human chorionic gonadotropin (hCG), pregnancy-specific beta-1-glycoprotein (SP1), and placental protein 5 (PP5) were measured prior to treatment in 14 patient with hydatidiform mole and in nine patients with choriocarcinoma. Measurement of circulating levels of SP1 and PP5, but not hCG, provides a distinction between benign and malignant gestational trophoblastic tumors.
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