These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Factors that control stem cell differentiation. II. The sensitivity of T-differentiated lymphocytes to the action of radiation and cytostatics].
    Author: Man'ko VM, Saiadian KhS, Khalatian NA.
    Journal: Tsitologiia; 1981 Mar; 23(3):333-9. PubMed ID: 6972648.
    Abstract:
    Bone marrow stem cells of the parent genotype (CBA) produce mainly erythroid colonies in the spleen of lethally irradiated recipients (CBA-C57Bl)F1. T d-lymphocytes change this differentiation pattern from the mainly erythroid to the mainly myeloid pathway. The irradiation with 100 R does not abolish this effect. The lymphocytes irradiated in vitro with 200 R or more, and incubated with Mitomycin C or Cycloheximide lost the ability to change the differentiation pattern of the transplanted cells. T d-lymphocytes are radiosensitive cells that need DNA and protein synthesis for realizing their function.
    [Abstract] [Full Text] [Related] [New Search]