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  • Title: Biochemical and immunological characterization of the major envelope glycoprotein of bovine leukemia virus.
    Author: Devare SG, Stephenson JR.
    Journal: J Virol; 1977 Aug; 23(2):443-7. PubMed ID: 69730.
    Abstract:
    The major envelope glycoprotein of bovine leukemia virus was isolated by lectin-bound Sepharose and DEAE-cellulose column chromatography. This protein was shown to have a molecular weight of about 41,000 and to lack detectable immunological cross-reactivity with glycoproteins of other oncornaviruses. Sera obtained from 100% of cattle examined with clinically diagnosed lymphosarcoma contained high-titered antibody to 125I-labeled bovine leukemia virus glycoprotein, whereas sera from animals in a disease-free herd were antibody negative.
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