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  • Title: [Electron microscopic study of reparative osteogenesis following electric stimulation of bony tissue regeneration].
    Author: Mikhaĭlova LN, Landa VA.
    Journal: Biull Eksp Biol Med; 1981 Jun; 91(6):719-22. PubMed ID: 6974018.
    Abstract:
    Electron microscopy was used to study the regenerating bone tissue in experimental resection of the diaphysis fragment of the rabbit radius under osteogenesis stimulation by means of pulsed low-frequency electric current. Proliferation and differentiation of fibroblasts and osteoblasts of the bone regenerating tissue were more active under electric stimulation. Hypertrophy and hyperplasia of cell organelles occurred earlier as compared with control. Cell secretion was found to be intensified, manifesting by output of greater amounts of collagen protein. As a result of changes listed, the newly formed bone tissue rapidly filled the defect between the fragments.
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