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  • Title: The influence of autologous erythrocytes on active T-cells rosetting with sheep red blood cells and on DNA synthesis.
    Author: Nowaczyk M, Skopińska-Rózewska E.
    Journal: Arch Immunol Ther Exp (Warsz); 1981; 29(3):391-6. PubMed ID: 6975089.
    Abstract:
    The addition of autologous erythrocytes to a mixture of human peripheral blood lymphocytes and sheep red blood cells (SRBC) alters the spontaneous rosetting reaction in the test detecting the active fraction of T lymphocytes (ARFC). Increase in rosetting is more often observed in mixtures containing smaller human red blood cell: lymphocyte ratios, while inhibition occurred in those containing a higher ratio. Autologous erythrocytes also affected DNA synthesis when added to three-day lymphocyte cultures, unstimulated or stimulated with BCG. These effects were more strongly pronounced when phagocytic cells were removed from lymphocytes tested.
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