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  • Title: The influence of the thymus on precursor T cells.
    Author: Kraal G, Boden D.
    Journal: Biomedicine; 1981 Sep; 35(4):115-9. PubMed ID: 6975129.
    Abstract:
    The influence of the thymus on its bone marrow precursors was investigated: T cell differentiation was studied in irradiated mice reconstituted with bone marrow from thymectomized donors. Up to twelve months after TX the influx of precursors and differentiation into T cells were not changed in the recipients. CFU-s determination of bone marrow and spleen from thymectomized animals did not show a change in numbers but during ageing a shift of the E/G ratio was observed in thymectomized as well as control donors.
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