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  • Title: [Demonstration of a subpopulation of T-lymphocytes by a monoclonal lymphocytotoxic antibody produced by cellular hybridization in slightly developed rheumatoid arthritis].
    Author: Mercier P, Dallest R, Garborit P, Blachère C, Roux H.
    Journal: Rev Rhum Mal Osteoartic; 1981 Oct; 48(10):621-5. PubMed ID: 6975497.
    Abstract:
    The lymphocytes from 20 cases of mild rheumatoid arthritis have been explored thanks to a monoclonal antibody found in a murine hybridoma of specificity I-E/Ck, "cross-reacting" with the human molecules HLA-DR+. A slight increase in the lymphocyte subpopulation T-DR+ is found, representing 25.15% versus 18.5% of the lymphocytes T isolated by rosettes in the normal subject. These cells correspond to a subpopulation of T lymphocytes whose immunologic function remains to be defined.
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