These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Age-dependent accumulation of thymic hormone-sensitive cells.
    Author: Kowalczyk D, Fournier M, Potworowski EF.
    Journal: Thymus; 1981 Dec; 3(6):335-43. PubMed ID: 6976650.
    Abstract:
    T-cell subsets were investigated in the thymus and spleen of BALB/c mice from 1 to 9 mth of age. It was found that in both of these organs, the proportion of T cells with a high surface concentration of Thy 1 antigen increased with age. The intensity of the graft-versus-host reaction induced by spleen and lymph node cells in F1 hybrids also increased with age. On the other hand, the response of thymocytes to Con A measured by migration inhibition decreased with age. All of these parameters could be reversed to the 1-mth-old levels by preincubation of the cells with a thymic hormone preparation. This indicates that in the time span under study, the changes observed could be attributed to an accumulation of thymic hormone-sensitive cells.
    [Abstract] [Full Text] [Related] [New Search]