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  • Title: Studies on the tissue specificity of the high-mobility-group non-histone chromosomal proteins from calf.
    Author: Rabbani A, Goodwin GH, Johns EW.
    Journal: Biochem J; 1978 Aug 01; 173(2):497-505. PubMed ID: 697733.
    Abstract:
    The high-mobility-group (HMG) non-histone chromosomal proteins from calf thymus, liver, spleen and kidney were extracted, and fractionated by CM-Sephadex chromatography and trichloroacetic acid precipitation. The isolated proteins HMG 1, HMG 2 and HMG 17 from the tissues were compared by polyacrylamide-gel electrophoresis, isoelectric focusing and amino acid analysis. The results show that the three proteins are very similar in the tissues studied, implying a lack of tissue specificity.
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