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  • Title: Differences in expression of MHC products between several H-2-restricted CTL clones.
    Author: Hauptfeld V, Braciale TJ, Shreffler DC.
    Journal: J Immunol; 1982 May; 128(5):2026-31. PubMed ID: 6977581.
    Abstract:
    Five cytotoxic T lymphocyte (CTL) clones, all specific for influenza virus A/JAP/57 and all H-2Kd-restricted, were typed for expression of MHC products. All express H-2K and H-2D encoded antigens, but they differ in their expression of I region products. One clone, 14-2, is positive with antisera directed against serologically detectable products apparently related to three different I regions, namely I-A, I-J, and I-E. Two clones, 11-1 and 14-1, lack I-E-associated antigens but express I-A and I-J products, and two other clones, 14-7 and 14-13, lack detectable I region products. These observations show that although discrete CTL clones may be homogeneous in their function, they differ in their expression of I region products.
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