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  • Title: The reaction of xenogeneic and monoclonal antisera with Reed-Sternberg cells.
    Author: Stuart AE, Jackson E, Morris CS.
    Journal: J Pathol; 1982 Jun; 137(2):129-38. PubMed ID: 6979620.
    Abstract:
    Xenogeneic antisera have been prepared against human monocytes, B lymphocytes and T lymphocytes. The reactivity of these antisera against a variety of normal and neoplastic cells is described. Reed-Sternberg cells from three cases of Hodgkin's disease failed to react with xenogeneic anti-T and anti-monocyte sera, but reacted with an anti-B serum. A further three cases were examined with monoclonal antibodies. Negative results were obtained with monoclonal anti-T and positive results were given by monoclonal antibodies directed against DR and HLA antigens.
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