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  • Title: The natural history of scoliosis in myelodysplasia.
    Author: Piggott H.
    Journal: J Bone Joint Surg Br; 1980 Feb; 62-B(1):54-8. PubMed ID: 6985915.
    Abstract:
    Two hundred and fifty cases of myelodysplasia were reviewed in relation to spinal deformity. Approximately half of the children had, or were expected to develop, curves severe enough to need operations and only 10 per cent maintained completely undeformed spines. The most frequent deformity was scoliosis which could be subdivided into congenital and developmental types. The latter was of mixed aetiology, neuromuscular imbalance and asymmetry of the neural arch both contributing, while in some cases no causative factors could be identified. The best early indicator that developmental scoliosis was likely to appear was a high segmental level of both the neurological deficit and the neural arch defect. Deformity was very unlikely to start after the age of nine years.
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