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  • Title: Effects of some antibacterial agents on the phagocytosis of 32P-labelled Escherichia coli by human polymorphonuclear cells.
    Author: Melby K, Midtvedt T.
    Journal: Acta Pathol Microbiol Scand B; 1980 Apr; 88(2):103-6. PubMed ID: 6990685.
    Abstract:
    Gentamicin, trimethroprim, cephalothin, colistin, erythromycin, oxytetracycline and chloramphenicol were studied in a phagocytic system. A radiolabelled strain of E. coli was used as test bacterium and human polymorphonuclear cells were used as phagocytes. Except for trimethoprim and cephalothin, there was a tendency towards depression of the process of phagocytosis in the presence of high concentrations of the various antibiotics. Colistin in a high concentration (83 micrograms/ml) exerted the most significant effect.
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