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  • Title: [Suppressive effect of bone marrow cells from normal and leukemic mice on antibody production in culture of spleen cells in vitro].
    Author: Sidorovich IG, Pcheliniev SIu, Khalmov RM.
    Journal: Biull Eksp Biol Med; 1980; 89(1):36-8. PubMed ID: 6991020.
    Abstract:
    The suppressive effect of bone marrow cells from AKR and (CBA X C57BL)F1 mice aged 2--10 months on the immune response of syngeneic spleen cells to sheep red blood cells in vitro was investigated. It was shown that the suppressive action of leukemic mice bone marrow cells greatly increases by the age of 9--10 months as compared to 2-month age. In (CBA X C57BL)F1 mice the suppressive acitivty of bone marrow remains unchanged over the same time period.
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