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  • Title: The effect of naftidrofuryl (Praxilene) on intermittent claudication.
    Author: Waters KJ, Craxford AD, Chamberlain J.
    Journal: Br J Surg; 1980 May; 67(5):349-51. PubMed ID: 6992910.
    Abstract:
    In a randomized double-blind controlled trial the effect of naftidrofuryl (Praxilene) 200 mg t.d.s., taken for 6 months, was compared with placebo in intermittent claudication. Whilst there was a significant subjective improvement regardless of age or treatment, patients over 60 on naftidrofuryl experienced a more rapid symptomatic relief than other patients. At six months this age group showed a significant improvement over the placebo group. There was no significnat objective evidence of improvement.
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