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Title: Signal sequences for early events in protein secretion and membrane assembly. Author: Lingappa VR, Lingappa JR, Blobel G. Journal: Ann N Y Acad Sci; 1980; 343():356-61. PubMed ID: 6994554. Abstract: Signal sequences for the transfer of proteins across membranes are usually found at the NH2-terminus of nascent secretory and transmembrane proteins. The functionally equivalent signal sequence of chicken ovalbumin however, is localized in the middle of the molecule. The implication of this surprising finding for biogenesis of membrane proteins is discussed.[Abstract] [Full Text] [Related] [New Search]