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  • Title: The prophylactic use of metronidazole in caesarean section.
    Author: McCowan L, Jackson P.
    Journal: N Z Med J; 1980 Aug 27; 92(666):153-5. PubMed ID: 7001295.
    Abstract:
    A double-blind study of 73 patients was undertaken to evaluate the prophylactic effect of short-term metronidazole in caesarean section. Metronidazole, 500 mg, given intravenously prior to making the incision, followed by 2 g, rectally, on completion of surgery failed to reduce the incidence of infection post-operatively. There was no reduction in the number of patients requiring antibiotics or in the quantity of post-operative pyrexia, as assessed by the fever index. The incidence of post-operative pyrexia was not affected by the duration of ruptured membranes or the use of a fetal scalp electrode.
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