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  • Title: [Ultrastructural characteristics of a monolayer cell culture of the guinea pig pancreatic islet apparatus].
    Author: Komissarenko VP, Gordienko VM, Turchin IS, Cherniavskaia IB.
    Journal: Tsitol Genet; 1980; 14(2):3-6. PubMed ID: 7003858.
    Abstract:
    A-, B- and D-insulocytes were revealed when studying the monolayer cell culture of guinea pig pancreatic islands with electron microscope. With an increase in cultivation time (3 days) the cytoplasm ultrastructure in all the cell types changes, the number of secretory granules in B-cells decreases. At later periods (10 days) the signs of secretory cells degeneration and dedifferentiation are observed.
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