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  • Title: Chronic lathyrism. Plasma, aorta and rat skin treated for five months with beta-aminopropionitrile with or without high fat diet.
    Author: Bouissou H, de Graeve J, Julian M, Pieraggi MT, Thiers JC.
    Journal: Pathol Biol (Paris); 1980 Dec; 28(10):645-50. PubMed ID: 7007998.
    Abstract:
    Previous experiments proved that white Wistar rats, resistant to spontaneous or experimental atheroma, present arteriosclerosis (parietal aorta lesions) and atheroma lesions (fat deposits) after a 9 week-treatment by Beta-aminopropionitrile (BAPN) followed by a high fat diet. The present work shows that BAPN alone, administered for 5 months, does not induced atheroma; its formation needs both lipid humoral disorders and parietal aortic lesions. It confirms certain facts noted in the aging of man and in the formation of atheroma.
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