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  • Title: Clinical experience with cefamandole in pneumonia.
    Author: Mattson K, Renkonen OV, Kohvakka A, Likitalo H.
    Journal: Scand J Infect Dis Suppl; 1980; suppl 25():103-6. PubMed ID: 7010534.
    Abstract:
    The efficacy and patient acceptance of i.m. cefamandole 1 000 mg 8 h and 500 mg 8 h, were compared in the treatment of assumed community-acquired pneumonia in 59 hospitalized adult patients. Of 31 patients treated with 1 000 mg 8 h, 94% had a satisfactory clinical response with a 13% bacteriological failure rate. Of 28 patients treated with 500 mg 8 h, 89% had a satisfactory clinical response with a 60% bacteriological failure rate. The only side effect registered was pain at the injection site after doses of more than 1 000 mg. The pain could be eliminated by the addition of 0.5 ml of lidocaine to the drug solution before injection.
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