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  • Title: [Oral treatment of lamellar ichthyosis (non-bullous congenital ichthyosiform erythroderma) with an aromatic retinoid (author's transl)].
    Author: Frenk E.
    Journal: Dermatologica; 1981; 162(2):91-103. PubMed ID: 7018943.
    Abstract:
    3 patients with lamellar ichthyosis have been treated orally with the aromatic retinoid Ro 10-9359 for periods of more than 2 years. This treatment resulted in a satisfactory improvement in the skin condition without any major side-effects. A light- and electron-microscopic study showed a marked decrease in the thickness of the lamellar stratum corneum without giving any clues concerning the mechanism of the therapeutic effect of this drug.
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