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  • Title: Characterization of insulin biosynthesis and secretion of pancreatic islets prepared from hyperglycaemic sand rats. II. Investigations of islets after different periods of cultivation.
    Author: Wilke B, Ziegler B, Besch W.
    Journal: Acta Biol Med Ger; 1981; 40(1):33-4. PubMed ID: 7020304.
    Abstract:
    Cultivation of pancreatic islets of sand rats in the presence of high glucose led to a very high insulin release and to strongly diminished insulin contents independent of the metabolic stage of the sand rats. Changes in the [3H]-leucine incorporation into (pro)insulin were not found in dependence of cultivation.
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