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  • Title: Yeast ochre suppressor SUQ5-ol is an altered tRNA Ser UCA.
    Author: Waldron C, Cox BS, Wills N, Gesteland RF, Piper PW, Colby D, Guthrie C.
    Journal: Nucleic Acids Res; 1981 Jul 10; 9(13):3077-88. PubMed ID: 7024909.
    Abstract:
    Ochre suppressor tRNA was partially purified from strains of Saccharomyces cerevisiae containing the serine-inserting class III suppressor SUQ5-ol. RNA sequence analysis of this tRNA indicated that the suppressor is derived from a UCA-decoding tRNA Ser by a G leads to U substitution in the middle position of the anticodon. The suppressor further differs from the wild-type UCA-decoding tRNA Ser in that the mutant anticodon lacks the modified uridine found in the wobble position of the wild-type tRNA and contains instead another modification in or near the anticodon.
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