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  • Title: Tiaprofenic acid (surgam) in the treatment of osteoarthritis of the knee and hip.
    Author: Wojtulewski J, Walter J, Thornton EJ.
    Journal: Rheumatol Rehabil; 1981 Aug; 20(3):177-80. PubMed ID: 7025176.
    Abstract:
    Tiaprofenic acid 200 mg three times a day was compared with indomethacin 25 mg three times a day in 36 patients suffering from osteoarthritis of the knee and hip. In this double-blind cross-over study little significant difference in efficacy between the drugs was seen. Although no significant difference in adverse effects was found, significantly fewer central nervous system side-effects were associated with tiaprofenic acid treatment.
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