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  • Title: [Dynamics of the phases of mitosis and the duration of cell division].
    Author: Dobrokhotov VN, Valvas VS.
    Journal: Biull Eksp Biol Med; 1981 Aug; 92(8):76-8. PubMed ID: 7028171.
    Abstract:
    A significant increase in the mean mitotic indices was found after adrenaline injection (2 micrograms/g) in the corneal epithelium of rat fetuses and in rats aged 3 to 4 days. This was accompanied by an appreciable rise in the number of metaphases, anatelophases and nucleus reconstruction, leading to an increase (by 3.7 times in fetuses; by 2.4 and 2 times in 3- and 4-day-old rats, respectively) in relative mitosis duration as compared to control animals. By the 10th day of postnatal development the differences in the magnitudes of the mitotic indices and relative mitosis duration completely disappeared. The method for appraising the relative duration of mitosis that occurs in response to varying exposures bases on a comparative analysis of the frequency of different mitotic phases was called "the time course of mitotic phases".
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