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  • Title: [Characteristics of the reaction of the embryonic hepatocyte to the effect of insulin and adrenaline].
    Author: Zabara AM, Kalinovskaia LP, Bariliak IR.
    Journal: Tsitol Genet; 1981; 15(5):8-14. PubMed ID: 7029832.
    Abstract:
    Adrenaline (10-6 g/ml) and insulin (10-6-8 IE/ml) cause changes of the acid DNase and phosphatase activity in hepatic cells of rat embryos on the 20th day of development. Adrenaline stimulates granular endoplasmatic reticulum development, increases the number and size of lysosomes, breaks their integrity. Insulin practically has no effect on the DNase activity, but labilizes the lysosome membrane.
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