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  • Title: [Mitotic regimen of different histological variants of lymphosarcoma].
    Author: Kazantseva IA, Probatova NA.
    Journal: Arkh Patol; 1981; 43(10):11-8. PubMed ID: 7032476.
    Abstract:
    Mitotic regimen of lymphosarcoma (75 observations), angiofollicular hyperplasia (5) and reactive hyperplasia of lymph nodes of the follicular type (34 observations--a group for comparison) was studied. The mitotic regimen values of non-Hodgkin's malignant lymphomas were found to vary in accordance with the morphological variant of the tumor. A higher mitotic activity in combination with high frequency and diversity of forms of mitosis pathology was typical of lymphoblast and immunoblast lymphosarcomas only. Prolymphocytic lymphosarcomas showed a relatively low mitotic activity. Lymphosarcoma with nodular growth showed a considerable decrease in mitotic activity as compared with nodular reactive hyperplasia. The emergence of multipolar mitoses is a reliable diagnostic sign of nodular lymphosarcoma.
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