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  • Title: [Repair and mutagenesis in Escherichia coli cells on induction in the DNA of monoadducts and cross-links by light-activated 8-methoxypsoralen. Dependence on the uvrA and polA genes].
    Author: Peshekhonov VT, Tarasov VA.
    Journal: Genetika; 1981; 17(11):1945-51. PubMed ID: 7033042.
    Abstract:
    Relative efficiency of (psoralen + near UV)-induced monoadducts and inter-strand cross-links of Escherichia coli cells has been studied, as well as the role of uvrA and polA genes in these processes. Inter-strand cross-links have been shown to be more effective, as compared with monoadducts both in cell inactivation and in mutagenesis. At least 3 ways for repair of DNA carrying monoadducts have been found, and only 2 for DNA carrying inter-strand cross-links, each of these being controlled by genes uvrA and polA in different modes.
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