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  • Title: [Serum pepsinogen: its value as index of basal and stimulated gastric acid secretion (author's transl)].
    Author: Florent C, Aymes C, Hirsch-Marie H, Rambaud JC.
    Journal: Nouv Presse Med; 1982 Jan 09; 11(1):35-7. PubMed ID: 7036088.
    Abstract:
    Group I pepsinogen serum levels (PG I) and gastric acid outputs were determined before ("basal") and after pentagastrin or insulin stimulation in 13 patients with active duodenal ulcer and in 4 patients with hyperselective vagotomy. There was a statistically significant correlation between basal PG I serum level and basal acid output (r = 0,88, p less than 0,01) and between PG I serum level 45 min after stimulation and peak acid output (r = 0,68, p less than 0,01). However, the scattering of individual values was such that serum PG I cannot be used as an index of gastric acid secretion in clinical practice.
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