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  • Title: Immunochemical and cytotoxic activities of Shigella dysenteriae 1 (shiga) and shiga-like toxins.
    Author: O'Brien AD, Laveck GD.
    Journal: Infect Immun; 1982 Mar; 35(3):1151-4. PubMed ID: 7040247.
    Abstract:
    Toxins in culture supernatants and bacterial lysates of S. dysenteriae 1 and S. flexneri were quantitated by a cytotoxicity assay and a newly developed radioimmunoassay. Cytotoxin titers paralleled toxin antigen levels. Thus, variations in cytotoxicity among shigellae probably reflect differences in toxin yield rather than specific activity (cytotoxicity per microgram of toxin antigen).
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