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  • Title: Salvage of the severely ischaemic limb by intra-arterial prostacyclin (PGI2) infusion. A case report.
    Author: Søreide O, Segadal L, Trippestad A, Engedal H.
    Journal: Scand J Thorac Cardiovasc Surg; 1982; 16(1):71-3. PubMed ID: 7041251.
    Abstract:
    A 75-year-old male patient with impending gangrene of the left lower limb due to advanced arteriosclerosis was treated with intra-arterial infusion of prostacyclin (PGI2). Pain at rest disappeared completely soon after treatment was started. Blood flow to the extremity measured by a Doppler velocity meter increased significantly during PGI2 infusion. Although some reduction in flow was found after termination of the infusion, the flow values up to 6 weeks after treatment were still markedly higher than pretreatment levels.
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